A Comparison of Cangrelor, Prasugrel, Ticagrelor, and Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention: A Network Meta-analysis

Newer P2Y12 inhibitors have more rapid onset of platelet inhibition compared with clopidogrel, especially the intravenous P2Y12 inhibitor cangrelor. Direct comparisons between cangrelor and oral P2Y12 inhibitors ticagrelor and prasugrel do not exist. Thus, we performed a network meta-analysis to directly and indirectly compare different P2Y12 inhibitors in patients undergoing percutaneous coronary intervention (PCI).

Source: Cardiovascular Revascularization Medicine - October 20, 2016 Category: Cardiology Authors: Peter C. Westman, Michael J. Lipinski, Rebecca Torguson, Ron Waksman Source Type: research