Impact of ornithine phenylacetate (OCR-002) in lowering plasma ammonia after upper gastrointestinal bleeding in cirrhotic patients

Conclusions:
OP failed to significantly decrease plasma ammonia at the given doses (10 g/day). Higher doses of OP might be required in Child–Pugh A and B patients. OP appeared well tolerated.

Source: Therapeutic Advances in Gastroenterology - October 20, 2016 Category: Gastroenterology Authors: Ventura-Cots, M., Concepcion, M., Arranz, J. A., Simon-Talero, M., Torrens, M., Blanco-Grau, A., Fuentes, I., Sune, P., Alvarado-Tapias, E., Gely, C., Roman, E., Minguez, B., Soriano, G., Genesca, J., Cordoba, J. Tags: Original Research Source Type: research