FISH-Microdissection

FISH-microdissection (FISH-MD) is an approach combining FISH technique and chromosome microdissection in one experiment. This method enables reliable and straightforward identification of target chromosomes or chromosomal regions by FISH with specific probes and immediate microdissection of the chromosomal region of interest. FISH-MD can be applied when chromosome identification by trypsin-Giemsa staining/banding is complicated or not possible due to chromosomal morphology.

Source: Springer protocols feed by Cell Biology - October 20, 2016 Category: Cytology Source Type: news