The fruit of Acanthopanax senticosus (Rupr. et Maxim.) Harms improves insulin resistance and hepatic lipid accumulation by modulation of liver adenosine monophosphate –activated protein kinase activity and lipogenic gene expression in high-fat diet–fed obese mice

Obesity-associated insulin resistance is a major risk factor for most metabolic diseases, including dyslipidemia and type 2 diabetes. Acanthopanax senticosus (Rupr. et Maxim.) Harms (Goka) root has been used in traditional Chinese medicine for treatment of diabetes and other conditions; however, little is known about the effects of Goka fruit (GF). Goka fruit is rich in anthocyanin, which has beneficial effects on obesity and insulin resistance via activation of adenosine monophosphate –activated protein kinase (AMPK).

Source: Nutrition Research - September 12, 2016 Category: Nutrition Authors: Tetsuo Saito, Miyako Nishida, Masafumi Saito, Akari Tanabe, Takahiro Eitsuka, Shi-Hua Yuan, Nobuo Ikekawa, Hiroshi Nishida Tags: Original Research Source Type: research