C-Terminal-Deleted Prion Protein Fragment Is a Major Accumulated Component of Systemic PrP Deposits in Hereditary Prion Disease With a 2-Bp (CT) Deletion in PRNP Codon 178

In conclusion, the mutated PrP lacking that GPI anchor was truncated shortly and deposited in almost every examined organ.

Source: Journal of Neuropathology and Experimental Neurology - October 17, 2016 Category: Neurology Authors: Honda, H., Matsuzono, K., Fushimi, S., Sato, K., Suzuki, S. O., Abe, K., Iwaki, T. Tags: Original Articles Source Type: research