Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery [Original Articles]

Conclusions—
The study provides the first high-resolution landscape on neonatal cardiac lncRNAs and reveals their potential interaction with mRNA transcriptome during cardiac maturation. Ppp1r1b-lncRNA was identified as a regulator of Tcap expression, with dynamic interaction in postnatal cardiac development and congenital heart defects.

Source: Circulation: Cardiovascular Genetics - October 17, 2016 Category: Cardiology Authors: Touma, M., Kang, X., Zhao, Y., Cass, A. A., Gao, F., Biniwale, R., Coppola, G., Xiao, X., Reemtsen, B., Wang, Y. Tags: Epigenetics, Gene Expression & Regulation, Functional Genomics Original Articles Source Type: research