Cellular Automaton Simulation of the Diffusive Motion of Bacteria and Their Adhesion to Nanostructures on a Solid Surface

The growth of a biofilm begins with the adhesion of bacteria to a solid surface. Consequently, biofilm growth can be managed by the control of bacterial adhesion. Recent experimental studies have suggested that bacterial adhesion can be controlled by modifying a solid surface using nanostructures. Computational prediction and analysis of bacterial adhesion behavior are expected to be useful for the design of effective arrangements of nanostructures for controlling bacterial adhesion. The present study developed a cellular automaton (CA) model for bacterial adhesion simulation that could describe both the diffusive motion of bacteria and dependence of their adhesion patterns on the distance between nanostructures observed in experimental studies.

Source: Computers in Biology and Medicine - October 16, 2016 Category: Bioinformatics Authors: Takehiro Yamamoto, Chie Emura, Masashi Oya Source Type: research