Urine metabolic profiling for the pathogenesis research of erosive oral lichen planus

Oral lichen planus (OLP) is a relatively common chronic immune-pathological and inflammatory disease and potentially oral precancerous lesion (Silverman, 2000). Its prevalence is between 0.5% and 3% (Herman& Sargi, 2013) and 0.5 –12.5% of OLP cases could encounter malignant transformation (Safadi, Al Jaber, Hammad,& Hamasha, 2010). OLP may affect any location in the oral cavity, whereas the oral mucosa, tongue and gingiva are the most common locations (Perdigao et al., 2007). OLP has three variants: the reticular, the plaque-like, and the erosive lesions.

Source: Archives of Oral Biology - October 16, 2016 Category: Dentistry Authors: Xu-zhao Li, Yang Xu-yan, Wang Yu, Shuai-nan Zhang, Zou Wei, Wang Yan, Li Xiao-nan, Wang Ling-shu, Zhi-gang Zhang, Xie Liang-zhen Source Type: research