Tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2, suppresses renal damage in KKAy/Ta mice, obese and type 2 diabetic animals

Conclusion:
Our present results demonstrated that tofogliflozin could suppress albuminuria and tubulointerstitial injury in obese and type 2 diabetic mice. Inhibition of glucose entry into tubular cells by tofogliflozin may exert renoprotective properties in diabetes.

Source: Diabetes and Vascular Disease Research - October 14, 2016 Category: Endocrinology Authors: Ishibashi, Y., Matsui, T., Yamagishi, S.-i. Tags: Brief Report Source Type: research