Preliminary Evaluation of the Effect of Investigational Ebola Virus Disease Treatments on Viral Genome Sequences

Conclusions. This small subset of patients and clinical specimens suggests that evolution of resistance is not a direct consequence of antiviral treatment. As EVD antiviral treatments are introduced into wider use, it is essential that continuous viral full-genome surveillance is performed, to monitor for the emergence of escape mutations.

Source: The Journal of Infectious Diseases - October 4, 2016 Category: Infectious Diseases Authors: Whitmer, S. L. M., Albarino, C., Shepard, S. S., Dudas, G., Sheth, M., Brown, S. C., Cannon, D., Erickson, B. R., Gibbons, A., Schuh, A., Sealy, T., Ervin, E., Frace, M., Uyeki, T. M., Nichol, S. T., Ströher, U. Tags: MEDICAL COUNTERMEASURES Source Type: research