Lateral Flow Immunoassays for Ebola Virus Disease Detection in Liberia

Conclusions. Rapid antigen-detection tests such as LFIs are attractive alternatives to traditional immunoassays but have reduced sensitivity and specificity, resulting in increases in false-positive and false-negative results. An understanding of the strengths, weaknesses, and limitations of a particular assay lets the diagnostician choose the correct situation to use the correct assay and properly interpret the results.

Source: The Journal of Infectious Diseases - October 4, 2016 Category: Infectious Diseases Authors: Phan, J. C., Pettitt, J., George, J. S., Fakoli, L. S., Taweh, F. M., Bateman, S. L., Bennett, R. S., Norris, S. L., Spinnler, D. A., Pimentel, G., Sahr, P. K., Bolay, F. K., Schoepp, R. J. Tags: DIAGNOSIS Source Type: research