Functional Diversity of Cytomegalovirus-Specific T Cells Is Maintained in Older People and Significantly Associated With Protein Specificity and Response Size

Discussion. Our results give a new perspective on T-cell polyfunctionality and raise the question of whether maintaining polyfunctionality of CMV-specific T cells at older ages is necessarily beneficial.

Source: The Journal of Infectious Diseases - October 12, 2016 Category: Infectious Diseases Authors: Bajwa, M., Vita, S., Vescovini, R., Larsen, M., Sansoni, P., Terrazzini, N., Caserta, S., Thomas, D., Davies, K. A., Smith, H., Kern, F. Tags: PATHOGENESIS AND HOST RESPONSE Source Type: research