Density, Serotype Diversity, and Fitness of Streptococcus pneumoniae in Upper Respiratory Tract Cocolonization With Nontypeable Haemophilus influenzae

Conclusions. Pneumococcal-NTHi cocolonization is associated with an elevated density of both species and with reduced diversity and increased fitness of pneumococcal serotypes. NTHi colonization may create a selective environment favoring pneumococci with immune-evasive phenotypes.

Source: The Journal of Infectious Diseases - October 12, 2016 Category: Infectious Diseases Authors: Lewnard, J. A., Huppert, A., Givon-Lavi, N., Pettigrew, M. M., Regev-Yochay, G., Dagan, R., Weinberger, D. M. Tags: BACTERIA Source Type: research