Chronic Hepatitis C Virus Infection and the Proinflammatory Effects of Injection Drug Use

Conclusions. Immune activation, a well-defined surrogate of poor clinical outcome that is elevated in PWID, can regress to normal levels in former injection drug users who are HCV aviremic. Therefore, enhanced harm-reduction efforts should incorporate aggressive treatment of HCV infection.
Clinical Trials Registration. NCT01831284.

Source: The Journal of Infectious Diseases - October 12, 2016 Category: Infectious Diseases Authors: Markowitz, M., Deren, S., Cleland, C., La Mar, M., Silva, E., Batista, P., St. Bernard, L., Gettie, N., Rodriguez, K., Evering, T. H., Lee, H., Mehandru, S. Tags: VIRUSES Source Type: research