Relationship Between HIV Coinfection, Interleukin 10 Production, and Mycobacterium tuberculosis in Human Lymph Node Granulomas

Conclusions. Peripheral CD4+ T-cell depletion correlated with increased M. tuberculosis presence, increased IL-10 production, and other phenotypic changes within granulomas, demonstrating the HIV infection progressively changes these granulomas.

Source: The Journal of Infectious Diseases - October 12, 2016 Category: Infectious Diseases Authors: Diedrich, C. R., O'Hern, J., Gutierrez, M. G., Allie, N., Papier, P., Meintjes, G., Coussens, A. K., Wainwright, H., Wilkinson, R. J. Tags: HIV/AIDS Source Type: research