Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo

Conclusions. We identified doses and dose schedules of a linezolid and moxifloxacin backbone regimen that could be highly efficacious in disseminated tuberculosis in children.

Source: Clinical Infectious Diseases - October 13, 2016 Category: Infectious Diseases Authors: Deshpande, D., Srivastava, S., Nuermberger, E., Pasipanodya, J. G., Swaminathan, S., Gumbo, T. Tags: A DEVELOPMENT PARADIGM FOR NOVEL COMBINATION REGIMENS FOR MULTIDRUG-RESISTANT AND DRUG-SUSCEPTIBLE TUBERCULOSIS IN CHILDREN: FLAME FOR WORK AND PLAY Source Type: research