Variable effects of chronic intermittent ethanol exposure on ethanol drinking in a genetically diverse mouse cohort

This study evaluated variations in the level of voluntary ethanol intake in a cohort of 42 BXD strains and both progenitor strains using a model of alcohol dependence and relapse drinking. A total of 119 BXDs (85 males, 34 females) (n  ∼ 4 per genotype; 1/genotype/sex/group) were evaluated along with males from both progenitor strains (n = 14–15/genotype).

Source: Alcohol - October 12, 2016 Category: Addiction Authors: Marcelo F. Lopez, Michael F. Miles, Robert W. Williams, Howard C. Becker Source Type: research