Recent Developments in Molecular Brain Imaging of Neuropsychiatric Disorders

Molecular imaging with PET or SPECT has been an important research tool in psychiatry for as long as these modalities have been available. Here, we discuss two areas of neuroimaging relevant to current psychiatry research. The first is the use of imaging to study neurotransmission. We discuss the use of pharmacologic probes to induce changes in levels of neurotransmitters that can be inferred through their effects on outcome measures of imaging experiments, from their historical origins focusing on dopamine transmission through recent developments involving serotonin, GABA, and glutamate.

Source: Seminars in Nuclear Medicine - October 12, 2016 Category: Nuclear Medicine Authors: Mark Slifstein, Anissa Abi-Dargham Source Type: research