A brief glimpse at CTRP3 and CTRP9 in lipid metabolism and cardiovascular protection

Publication date: Available online 12 October 2016 Source:Progress in Lipid Research Author(s): Yang Yang, Yue Li, Zhiqiang Ma, Shuai Jiang, Chongxi Fan, Wei Hu, Dongjin Wang, Shouyin Di, Yang Sun, Wei Yi Adipose tissue is now known to express and secrete numerous adipokines that not only regulate lipid metabolism but also function in a wide array of physiological or pathological processes. C1q tumor necrosis factor-related protein 3 (CTRP3, also known as CORS26/cartducin) and CTRP9, novel members of the adipokine family, have intersecting functions in the regulation of lipid metabolism and contribute to cardiovascular protection. Here, we focus on the novel advances concerning the roles of CTRP3 and CTRP9 in these processes and review the general mechanisms. This review should serve as a basis for the design of future experimental studies and may implicate these adipokines as future therapeutic targets.

Source: Progress in Lipid Research - October 12, 2016 Category: Lipidology Source Type: research