ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment

In conclusion, this study identifies ARL3 as a key player in prenylated protein trafficking in rod photoreceptor cells and establishes the potential role for ARL3 dysregulation in the pathogenesis of RP2-related forms of XLRP.

Source: Human Molecular Genetics - October 12, 2016 Category: Genetics & Stem Cells Authors: Wright, Z. C., Singh, R. K., Alpino, R., Goldberg, A. F. X., Sokolov, M., Ramamurthy, V. Tags: ARTICLES Source Type: research