Pravastatin Effects on Placental Prosurvival Molecular Pathways in a Mouse Model of Preeclampsia
Conclusion:
Pravastatin ability to prevent preeclampsia phenotype may be mediated through pleiotropic mechanisms involving a prosurvival/ antiapoptotic MAPK pathway in the placenta. Our results further support continued research in the role for statins in the prevention of preeclampsia.
Source: Reproductive Sciences - Category: Reproduction Medicine Authors: Saad, A. F., Diken, Z. M., Kechichian, T. B., Clark, S. M., Olson, G. L., Saade, G. R., Costantine, M. M. Tags: Original Articles Source Type: research
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