Molecular structure and differential function of choline kinases CHK α and CHKβ in musculoskeletal system and cancer

Choline, a charged hydrophilic cation, plays an important role in various organs and cells throughout the body, including cholinergic neurotransmission, memory consolidation and as a critical component of cell membranes. Choline is an essential nutrient and can be produced within the body through the degradation of choline containing phospholipids. However, this source is insufficient to maintain choline levels and dietary intake of choline is necessary to prevent choline-deficiency associated liver and muscle damage [1].
Source: Cytokine and Growth Factor Reviews - Category: Molecular Biology Authors: Source Type: research