Octreotide and pasireotide (dis)similarly inhibit pituitary tumor cells in vitro

In conclusion, both SSA act in vitro on pituitary adenomas exerting both similar and distinct effects; however, no evident correspondence was found with the sst1-sst5 profile. Thus, it seems plausible that additional factors, besides the simple abundance of a given sst, critically influence the SSA response.

Source: Journal of Endocrinology - October 5, 2016 Category: Endocrinology Authors: Ibanez-Costa, A., Rivero-Cortes, E., Vazquez-Borrego, M. C., Gahete, M. D., Jimenez-Reina, L., Venegas-Moreno, E., de la Riva, A., Arraez, M. A., Gonzalez-Molero, I., Schmid, H. A., Maraver-Selfa, S., Gavilan-Villarejo, I., Garcia-Arnes, J. A., Japon, M. Tags: Research Source Type: research