Association of nadir oxygen delivery on cardiopulmonary bypass with serum glial fibrillary acid protein levels in paediatric heart surgery patients

CONCLUSIONS
Lower nadir DO2 is associated with increased GFAP levels, suggesting that diminished DO2 during paediatric heart surgery may be contributing to neurological injury. The DO2–GFAP relationship may provide a useful measure for the implementation of neuroprotective strategies in paediatric heart surgery, including goal-directed perfusion.

Source: Interactive CardioVascular and Thoracic Surgery - September 25, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Magruder, J. T., Hibino, N., Collica, S., Zhang, H., Harness, H. L., Heitmiller, E. S., Jacobs, M. L., Cameron, D. E., Vricella, L. A., Everett, A. D. Tags: Extracorporeal circulation, Mechanical Circulatory Assistance Congenital Source Type: research