The influence of renal transplantation on retained microbial-human co-metabolites

Conclusions Colonic microbiota-derived uraemic retention solutes substantially decrease following renal transplantation. The 24-h urinary excretion of these microbial–human co-metabolites is lower when compared with CKD patients, suggesting an independent influence of transplantation on intestinal uptake, a composite of colonic microbial metabolism and intestinal absorption. Renal solute handling may differ between transplant recipients and CKD patients.

http://ndt.oxfordjournals.org/cgi/content/short/31/10/1721?rss=1

Source: Nephrology Dialysis Transplantation - September 27, 2016 Category: Urology & Nephrology Authors: Poesen, R., Evenepoel, P., de Loor, H., Bammens, B., Claes, K., Sprangers, B., Naesens, M., Kuypers, D., Augustijns, P., Meijers, B. Tags: Renal Transplantation Source Type: research