Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy

Conclusions. Elevated cholesterol and APOE 4 genotype are independent risk factors for cognitive decline in ART-adherent HIV+ men aged >50 years. Treatment of dyslipidemia may be an effective strategy to reduce cognitive decline in older HIV+ individuals.

Source: Clinical Infectious Diseases - September 25, 2016 Category: Infectious Diseases Authors: Mukerji, S. S., Locascio, J. J., Misra, V., Lorenz, D. R., Holman, A., Dutta, A., Penugonda, S., Wolinsky, S. M., Gabuzda, D. Tags: HIV/AIDS Source Type: research