Ribavirin-Free Regimen With Sofosbuvir and Velpatasvir Is Associated With High Efficacy and Improvement of Patient-Reported Outcomes in Patients With Genotypes 2 and 3 Chronic Hepatitis C: Results From Astral-2 and -3 Clinical Trials

Conclusions. Patients receiving ribavirin-free SOF/VEL reported significantly better PRO scores during treatment compared with those receiving the RBV-containing regimen. Furthermore, the interferon- and ribavirin-free SOF/VEL regimen resulted in a rapid improvement of PROs in HCV GTs 2 and 3 patients during treatment and after achieving sustained virologic response.

Source: Clinical Infectious Diseases - September 25, 2016 Category: Infectious Diseases Authors: Younossi, Z. M., Stepanova, M., Sulkowski, M., Foster, G. R., Reau, N., Mangia, A., Patel, K., Bräu, N., Roberts, S. K., Afdhal, N., Nader, F., Henry, L., Hunt, S. Tags: ARTICLES AND COMMENTARIES Source Type: research