Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia

In conclusion, parenteral Leu supplementation attenuates the LPS-induced reduction in PS by stimulating mammalian target of rapamycin complex 1-dependent translation and may reduce PD by attenuating autophagy-lysosome and MuRF-1 signaling in neonatal skeletal muscle.

Source: AJP: Endocrinology and Metabolism - October 4, 2016 Category: Endocrinology Authors: Hernandez-Garcia, A. D., Columbus, D. A., Manjarin, R., Nguyen, H. V., Suryawan, A., Orellana, R. A., Davis, T. A. Tags: Articles Source Type: research