Insulin does not stimulate muscle protein synthesis during increased plasma branched-chain amino acids alone but still decreases whole body proteolysis in humans

In conclusion, insulin does not stimulate muscle protein synthesis in the presence of increased circulating levels of plasma BCAA alone. Insulin's suppressive effect on proteolysis is observed independently of the levels of circulating plasma BCAA.

Source: AJP: Endocrinology and Metabolism - September 30, 2016 Category: Endocrinology Authors: Everman, S., Meyer, C., Tran, L., Hoffman, N., Carroll, C. C., Dedmon, W. L., Katsanos, C. S. Tags: Articles Source Type: research