High Fructose Corn Syrup-55 Consumption Alters Hepatic Lipid Metabolism and Promotes Triglyceride Accumulation

High fructose corn syrup-55 (HFCS-55) has been suggested to be more lipogenic than sucrose which increases the risk for non-alcoholic fatty liver disease (NAFLD) and dyslipidemia. The study objectives were to determine the effects of drinking different sugar-sweetened solutions on hepatic gene expression in relation to liver fatty acid composition and risk of NAFLD. Female rats were randomly assigned (n=7 rats/group) to drink water or water sweetened with either 13% (w/v) HFCS-55, sucrose or fructose for 8 weeks.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research