Researchers find a gap in the brain ’s firewall against Parkinson’s disease

In a study in mice, researchers found that they could reduce the progression of the toxic aggregates of α-synuclein that are found in the brains of Parkinson’s disease patients. The results suggest that a protein called lymphocyte-activation gene 3 (LAG3) plays a role in transmitting α-synuclein aggregates from one brain cell to another and could provide a possible target to slow the progression o f Parkinson’s disease. The study, published in Science, was partially funded by the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NINDS).
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - Category: Neurology Source Type: news