Radiolabeling and Biological Characterization of TPGS-based Nanomicelles by Means of Small Animal Imaging

In recent years, nanomedicines have raised as a powerful tool to improve prevention, diagnosis and treatment of different pathologies. Among the most well investigated biomaterials, D- α-tocopheryl polyethylene glycol succinate (also known as TPGS) has been on the spot for the last decade. We therefore designed a method to biologically characterize TPGS-based nanomicelles by labeling them with 99mTc.

Source: Nuclear Medicine and Biology - September 29, 2016 Category: Nuclear Medicine Authors: Fiorella Carla Tesan, Mariano Gast ón Portillo, Marcela Analía Moretton, Ezequiel Bernabeu, Diego Andrés Chiappetta, Maria Jimena Salgueiro, Marcela Beatriz Zubillaga Source Type: research