Genetic variation of MMP ‐2(‐735 C > T) and MMP ‐9(‐1562 C > T) gene in risk of development of HAND and severity of HAND

ConclusionsIndividuals with the MMP‐2 ‐735CT genotype, −735 T allele and combined genotype MMP‐2 ‐735TT + MMP‐9 ‐1562CC had an enhanced risk of developing HAND. Those with the MMP‐2 ‐735 CT genotype, −735 T allele and combined genotype of MMP‐2‐735TT + MMP‐9‐1562CC were suggested to have protection from developing severe HAND.
Source: The Journal of Gene Medicine - Category: Genetics & Stem Cells Authors: Tags: RESEARCH ARTICLE Source Type: research