Lentiviral HSV ‐Tk.007‐mediated suicide gene therapy is not toxic for normal brain cells

ConclusionsWe show that HSV‐Tk.007‐mediated suicide gene therapy is not toxic to normal brain cells. This observation is of high relevance for the translation of lentivirus‐mediated suicide gene therapies into the clinic for the treatment of brain tumor patients. Copyright © 2016 John Wiley & Sons, Ltd.

Source: The Journal of Gene Medicine - September 26, 2016 Category: Genetics & Stem Cells Authors: Jubayer A. Hossain, Lars R ømo Ystaas, Jelena Mrdalj, Kristjan Välk, Kristoffer Riecken, Boris Fehse, Rolf Bjerkvig, Janne Grønli, Hrvoje Miletic Tags: Research Article Source Type: research