Life and death rest on a bivalent chromatin state
Nature Neuroscience 19, 1271 (2016).
doi:10.1038/nn.4396
Author: X William Yang
Neurons require lifelong maintenance of their transcriptional program, which includes stable expression of cell-type-specific identity genes. A study now shows that PRC2-mediated chromatin repression in adulthood is critical for the maintenance of neuronal identity gene expression and neuronal survival.
Source: Nature Neuroscience - Category: Neuroscience Authors: X William Yang Tags: News and Views Source Type: research