Immunotherapy in breast cancer: An overview of modern checkpoint blockade strategies and vaccines

Immune therapy has recently emerged as a standard-of-care strategy for the treatment of melanoma, lung cancer, bladder cancer, among other malignancies. However, the role of immune therapy in the treatment of breast cancer is still being determined. Two current strategies for harnessing the immune system to treat cancer include drugs that modulate key T cell inhibitory checkpoints and vaccines. Specifically, modern immune therapy strategies can facilitate T-cell mediated tumor regression by priming the immune system against specific tumor associated antigens, by modulating immunoregulatory signals, or both.
Source: Current Problems in Cancer - Category: Cancer & Oncology Authors: Tags: Massarweh: Breast Cancer Source Type: research