N-[18F]-FluoropropylJDTic for κ-Opioid Receptor PET Imaging: Radiosynthesis, Pre-clinical Evaluation, and Metabolic Investigation in Comparison with Parent JDTic

To image kappa opioid receptor (KOR) for preclinical studies, N-fluoropropylJDTic 9 derived from the best-established KOR antagonist JDTic, was labeled with fluorine-18.

Source: Nuclear Medicine and Biology - September 25, 2016 Category: Nuclear Medicine Authors: S ébastien Schmitt, Jérôme Delamare, Olivier Tirel, Fabien Fillesoye, Martine Dhilly, Cécile Perrio Source Type: research