DNA Vaccination as a Treatment for Chronic Kidney Disease

Chronic kidney disease is one of the major health problems worldwide. DNA vaccination delivers plasmid DNA encoding the target gene to induce both humoral and cellular immune responses. Here, we describe the methods of CD40 DNA vaccines enhanced by dendritic cell (DC) targeting on the development of Heymann nephritis (HN), a rat model of human membranous nephropathy.
Source: Springer protocols feed by Immunology - Category: Allergy & Immunology Source Type: news