Octreotide: The IIH therapy beyond weight loss, carbonic anhydrase inhibitors, lumbar punctures and CSF shunting

Pseudotumor cerebri syndrome (PTCS) may be primary or secondary. Secondary PTCS arises from an identifiable cause like cerebral venous abnormalities, various medications and exposures, as well as medical conditions like endocrine disorders (Addison disease, hypoparathyroidism), hypercapnia (sleep apnea, Pickwickian syndrome), anemia, renal failure, Turner syndrome and Down syndrome [1]. Primary PTCS is also called idiopathic intracranial hypertension (IIH), formerly also pseudotumor cerebri. IIH is a condition characterized by elevated intracranial pressure without a space-occupying cerebral lesion, venous sinus thrombosis or hydrocephalus and with a normal composition of cerebrospinal fluid (CSF).

Source: Clinical Neurology and Neurosurgery - September 23, 2016 Category: Neurosurgery Authors: Patrick M. House, Stefan R.G. Stodieck Source Type: research