Alterations in Systemic Extracellular Heme and Hemopexin Are Associated With Adverse Clinical Outcomes in Ugandan Children With Severe Malaria

Conclusions. The ratio of heme to hpx is associated with disease severity and adverse clinical outcomes in Ugandan children, and dysregulation of the heme axis may contribute to malaria pathogenesis.

Source: The Journal of Infectious Diseases - September 22, 2016 Category: Infectious Diseases Authors: Elphinstone, R. E., Conroy, A. L., Hawkes, M., Hermann, L., Namasopo, S., Warren, H. S., John, C. C., Liles, W. C., Kain, K. C. Tags: PATHOGENESIS AND HOST RESPONSE Source Type: research