Serine and one-carbon metabolism in cancer
Nature Reviews Cancer 16, 650 (2016).
doi:10.1038/nrc.2016.81
Authors: Ming Yang & Karen H. Vousden
The non-essential amino acid serine supports several metabolic processes that are crucial for the growth and survival of proliferating cells, including protein, amino acid and glutathione synthesis. As an important one-carbon donor to the folate cycle, serine contributes to nucleotide synthesis, methylation reactions and the
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Ming Yang Karen H. Vousden Tags: Review Source Type: research
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