From Krebs to clinic: glutamine metabolism to cancer therapy

Nature Reviews Cancer 16, 619 (2016). doi:10.1038/nrc.2016.71 Authors: Brian J. Altman, Zachary E. Stine & Chi V. Dang The resurgence of research into cancer metabolism has recently broadened interests beyond glucose and the Warburg effect to other nutrients, including glutamine. Because oncogenic alterations of metabolism render cancer cells addicted to nutrients, pathways involved in glycolysis or glutaminolysis could be exploited for therapeutic purposes.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research