Genetics: Transcribing for the enemy

Nature Reviews Cancer 16, 617 (2016). doi:10.1038/nrc.2016.104 Author: M. Teresa Villanueva Clark et al. carried out genomic analyses of 775 meningiomas and found recurrent mutations in POLR2A, which encodes the catalytic subunit of RNA polymerase II, an essential enzyme that mediates the transcription of all protein-coding genes in eukaryotic cells. Mutant POLR2A allows
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research