Tumour metabolism: Metabolic flexibility

Nature Reviews Cancer 16, 617 (2016). doi:10.1038/nrc.2016.101 Author: Anna Dart Glutamine supports cancer cell growth, yet cancer cells can survive glutamine depletion. Reid et al. reveal a novel pathway exploited by tumours to adapt to glutamine starvation through the activation of inhibitor of nuclear factor-κB (NF-κB) kinase subunit-β (IKKβ). Independently of inducing NF-κB transcriptional
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research