Tumour metabolism: Adapting to harsh conditions

Nature Reviews Cancer 16, 616 (2016). doi:10.1038/nrc.2016.98 Author: Sarah Seton-Rogers Chae et al. show that mitochondrially-localized AKT phosphorylates pyruvate dehydrogenase kinase 1 (PDK1) to promote tumour cell growth and survival in hypoxic conditions.

http://feeds.nature.com/~r/nrc/rss/current/~3/btDtFeaW-t0/nrc.2016.98

Source: Nature Reviews Cancer - August 25, 2016 Category: Cancer & Oncology Authors: Sarah Seton-Rogers Tags: Research Highlight Source Type: research

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