Mineralocorticoid receptor haplotype moderates the effects of oral contraceptives and menstrual cycle on emotional information processing

Conclusion:
MR-haplotype 1/3 carriers may be more sensitive to the influence of their female hormonal status. MR-haplotype 2 carriers showed more risky decision-making. As this may reflect optimistic expectations, this finding may support previous observations in female carriers of MR-haplotype 2 in a naturalistic cohort study.

Source: Journal of Psychopharmacology - September 22, 2016 Category: Psychiatry Authors: Hamstra, D. A., de Kloet, E. R., Tollenaar, M., Verkuil, B., Manai, M., Putman, P., Van der Does, W. Tags: Original Papers Source Type: research