Mulberry fruit ameliorates Parkinson's disease-related pathology by reducing α-synuclein and ubiquitin levels in an 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model

Mulberry fruit, which has been long used in traditional oriental medicine, was reported to ameliorate motor dysfunction and dopaminergic neuronal degeneration via antioxidant and anti-apoptotic effects in an animal model of Parkinson's disease (PD).>95% of PD patients exhibit non-motor problems such as olfactory dysfunction and gastrointestinal constipation, which are generally considered to be early symptoms of PD. However, few studies have actually examined potential drugs to treat early PD symptoms.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research