Genetic Predisposition to Endocrine Tumors: Diagnosis, Surveillance and Challenges in Care

Endocrine tumor syndromes, e.g. Multiple Endocrine Neoplasia type 1& 2, were among the first recognized hereditary predisposition syndromes to tumor development. Over time, the number of endocrine tumor syndromes has significantly expanded, e,g, with the recent inclusion of Hereditary Paraganglioma Syndromes. Associations of non-endocrine tumors with hereditary endocrine tumor syndromes and endocrine tumors with non-classical endocrine tumor syndromes have emerged. These findings have certainly expanded the scope of care, necessitating a multidisciplinary approach by a team of medical professionals and researchers, integrating shared patient decision-making at every step of surveillance, diagnosis and treatment.

Source: Seminars in Oncology - September 20, 2016 Category: Cancer & Oncology Authors: Elisabeth Joye Petr, Tobias Else Source Type: research