Cancer biology: Hypoxia as an off switch for gene expression

Nature Reviews Molecular Cell Biology 17, 610 (2016). doi:10.1038/nrm.2016.119 Author: Paulina Strzyz A new study shows that hypoxia interferes with DNA demethylation, resulting in DNA hypermethylation and repression of gene expression, which in tumours leads to the silencing of tumour suppressors.

http://feeds.nature.com/~r/nrm/rss/current/~3/_Vb5kyy5gA8/nrm.2016.119

Source: Nature Reviews Molecular Cell Biology - August 31, 2016 Category: Cytology Authors: Paulina Strzyz Tags: Research Highlight Source Type: research