mRNA expression profiles of colorectal liver metastases as a novel biomarker for early recurrence after partial hepatectomy

Identification of specific risk groups for recurrence after surgery for isolated colorectal liver metastases (CRLM) remains challenging due to the heterogeneity of the disease. Classical clinicopathologic parameters have limited prognostic value. The aim of this study was to identify a gene expression signature measured in CRLM discriminating early from late recurrence after partial hepatectomy.

Source: Molecular Oncology - September 18, 2016 Category: Cancer & Oncology Authors: E.P. van der Stok, M. Smid, A.M. Sieuwerts, P.B. Vermeulen, S. Sleijfer, N. Ayez, D.J. Gr ünhagen, J.W.M. Martens, C. Verhoef Source Type: research